LIPTIDE: THE ARTIFICIAL VIRUS
LipTide’s peptides bind the payload at its core and protrude from the surface, enabling them to engage with receptors abundant on specific cells.
This peptide-receptor binding triggers the cell to take in the nanoparticle. Once inside the cell, the lipid component of LipTide enables rapid and effective release of the nucleic acid payload.
The targeted delivery holds the key to LipTide’s groundbreaking potential, providing:
Higher delivery rates and specificity than traditional liposomal vectors
Greater versatility and lower safety risks than viral vectors
High tolerability making it suitable for regular repeat dosing
THE VECTOR CUSTOM-BUILT FOR YOU
LipTide is a flexible delivery system. Different surface peptides can be used to bind with different types of target cell. Different administration methods can be used, such as injection into the bloodstream or inhalation into the lungs.
siRNA, mRNA or any nucleic acid including DNA and gene editing capability
Active uptake in
the right part
of the body
DELIVERING IN PRACTICE
LipTide has successfully delivered gene therapy across a broad range of applications. We are now taking this exciting in vivo data forward to the clinic.
Targeted delivery to tumours
without leakage to other
organs, especially the liver
Delivery to airway
epithelial cells via
Repeat airway and
systemic delivery achieving
Ocular delivery to
ensure success of
Effective suppression of
tumour growth by silencing
a key oncogene
Optimised delivery of siRNA payloads
Altogether Lip Tide contains all of the components for efficient, targeted and well-tolerated delivery, bringing the full potential of gene silencing, gene enhancement or even gene editing therapeutics within reach.